Latifah, Nur (2018) AKTIVITAS GEL EKSTRAK RIMPANG KUNYIT (Curcuma domestica Val) TERHADAP BAKTERI Staphylococcus aureus. Undergraduate thesis, Stikes Karya Putra Bangsa Tulungagung.
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Abstract
Indonesia is a country that has various medicinal herbs. One type of medicinal plant that is often used for treatment is the turmeric rhizome. Turmeric rhizome contains alkaloid compounds, tannins and flavonoids.This research was conducted in vitro to investigate the activity both of turmeric extract and gel from turmeric extract against S. aureususing disk diffusion method. The extraction turmeric from turmeric rhizome was performed by soxhlet method using 96% ethanol as solvent. We varied the concentration of turmeric extract such as 45%, 55%, 65% and 75%. The optimum concentration which has high bacterrial activity was applied in gel formulation.The results of this study indicate that turmeric extract 45% exhibited strong antibacterial activity against S.aureuswith inhibition zone diameter of 11 mm. Other concentrations of 55%, 65% and 75% gave inhibition zone diameter of 10, 10,5and 10,1 respectively. Gel was formulated using 45 % turmeric extract.The gel generated antibacterial activity of 19 mm in inhibition zone diameter. Evaluation of gel showed a good result such as organoleptic, homogeneity, pH, spreading capacity test in accordance with the standard of gel preparation. However, the adhesion and gel stability test are not favorablein relative to the standard gel preparation. Keywords: Turmeric extract, soxhlet method, gel, S. aureus.
| Item Type: | Thesis (Undergraduate) |
|---|---|
| Uncontrolled Keywords: | Turmeric extract, soxhlet method, gel, S. aureus. |
| Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry Q Science > QR Microbiology |
| Divisions: | Program Studi > S1 Farmasi |
| Depositing User: | Surya Hadi Prasetyo |
| Date Deposited: | 24 Jan 2022 04:08 |
| Last Modified: | 24 Jan 2022 04:08 |
| URI: | http://repository.stikes-kartrasa.ac.id/id/eprint/39 |
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