UJI AKTIVITAS ANTIBAKTERI FRAKSI DARI MASERAT Zibethinus folium TERHADAP Escherichia coli

Huda, Choirul and Putri, Amalia Eka and Sari, Devri Windi (2019) UJI AKTIVITAS ANTIBAKTERI FRAKSI DARI MASERAT Zibethinus folium TERHADAP Escherichia coli. Jurnal SainHealth, 3 (1). pp. 40-45. ISSN 2548-8333

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Abstract

Durian leaf (Zibethinus folium) is part of the plant that has antibacterial activity. The purpose of this study was to determine the antibacterial activity of Zibethinus folium fraction against Escherichia coli ATCC 25922 in vitro. The research method used is experimental. Leaf samples were extracted using maceration method with 70% ethanol and purified by fractionation methods using aqua distilled, n-hexane, and ethyl acetate. Positive control is clindamycin gel and negative control is 5% DMSO. Statistical analysis was performed with One-Way Anova. Phytochemical screening results show that macerate Zibethinus folium contains flavonoids, tannins, saponins and steroids. The test results of antibacterial activity aqua distilled fraction and ethyl acetate fraction of macerate Zibethinus folium shows antibacterial activity against Escherichia coli ATCC 25922, while the n-hexane fraction of macerate Zibethinus folium showed no antibacterial activity against Escherichia coli ATCC 25922. aqua distilled fraction of 40% showed a response the most well barriers with zone of inhibition 8.33 ± 0.76 mm, meaning that aqua distilled fraction of 40% including medium category. Keywords: Zibethinus folium, maceration, fractionation, antibacterial, Escherichia coli

Item Type:	Article
Uncontrolled Keywords:	Zibethinus folium, maceration, fractionation, antibacterial, Escherichia coli
Subjects:	R Medicine > R Medicine (General) R Medicine > RS Pharmacy and materia medica R Medicine > RV Botanic, Thomsonian, and eclectic medicine S Agriculture > S Agriculture (General)
Divisions:	Program Studi > S1 Farmasi
Depositing User:	Surya Hadi Prasetyo
Date Deposited:	01 Dec 2022 06:57
Last Modified:	01 Dec 2022 06:57
URI:	http://repository.stikes-kartrasa.ac.id/id/eprint/9

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