Cahyaningrum, Betty Dwi (2018) UJI AKTIVITAS ANTIJAMUR KOMBINASI EKSTRAK ETANOL 70% DAUN KERSEN (Muntingia calabura L.) DAN DAUN SUKUN (Artocarpus communis Forst.) TERHADAP Candida albicans. Undergraduate thesis, Stikes Karya Putra Bangsa Tulungagung.
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Abstract
Candida albicans is normal flora living in the body that can cause candidiasis vulvovaginalis desease in the genital region. The treatment of candidiasis vulvovaginalis desease was applied with antifungal drug which continue with another impact such as antifungal drug resistance in long period of aplication. Jamaica cherry (Muntingia calabura L.) and breadfruit (Artocarpus communis Forst.) have been known in Indonesia. The leaves of jamaica cherry and breadfruit have been applied as traditional medicine. The purpose of this study are to determine the antifungal activity of combination from 70% ethanol extract of jamaica cherry and breadfruit leaves extract with three ratios (v/v) of 25: 75 (jamaica cherry leaves: breadfruit leaves), 50: 50 (jamaica cherry leavest: breadfruit leaves), 75: 25 (jamica cherry leaves: breadfruit leaves). The antifungal activity was performed by disc diffusion method. Ketoconazole 2% was used as positive control and DMSO was is used as negative control. The results showed the three such combinations generated minimum inhibitory diamater zone of 8 mm, 8.5 mm, and 10 mm, respectively. The positive control produced inhibitory zone of 30 mm, and negative control has no inhibitory zone. Combination 25: 75 is an optimum combination for jamica cherry leaves extract: breadfruit leaves extract. Keywords: Candida albicans, Muntingia calabura L., Artocarpus communis Forst., Antifungal, Ethanol 70%.
| Item Type: | Thesis (Undergraduate) |
|---|---|
| Uncontrolled Keywords: | Candida albicans, Muntingia calabura L., Artocarpus communis Forst., Antifungal, Ethanol 70%. |
| Subjects: | Q Science > Q Science (General) R Medicine > R Medicine (General) |
| Divisions: | Program Studi > S1 Farmasi |
| Depositing User: | Surya Hadi Prasetyo |
| Date Deposited: | 11 Jan 2022 04:28 |
| Last Modified: | 11 Jan 2022 04:28 |
| URI: | http://repository.stikes-kartrasa.ac.id/id/eprint/18 |
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