UJI AKTIVITAS ANTIBAKTERI GEL FRAKSI DARI EKSTRAK SOKHLET Zibethinus folium TERHADAP Staphylococcus areus SECARA IN VITRO

Azizah, Dahniar Husnawiyatul (2018) UJI AKTIVITAS ANTIBAKTERI GEL FRAKSI DARI EKSTRAK SOKHLET Zibethinus folium TERHADAP Staphylococcus areus SECARA IN VITRO. Undergraduate thesis, Stikes Karya Putra Bangsa Tulungagung.

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Abstract

The aim of this research is to find out antibacterial activity, optimum concentration and antibacterial activity of fractional gel from Zibethinus folium extract (Durian Leaf) against Staphylococcus aureus bacterial inhibition. The extraction was performed by sochletation method using 70% ethanol solvent followed by fractionation with aqua distillate, ethyl acetate and n-hexane solvent. Test antibacterial activity using agar diffusion method. The parameters measured were the amount of inhibitory power in the growth of Staphylococcus aureus formed around the disc paper. The results of antibacterial activity test were analyzed using One Way Anova method followed by Two-Sample T-Test. The results showed that the effective concentrations inhibiting Staphylococcus aureus were 5%, 15%, and 30%. The optimum result on the fraction was obtained at ethyl acetate fraction with 30% concentration with mean of 22.8 mm inhibition diameter. The results of the gel studies showed that effective concentrations inhibiting Staphylococcus aureus were 0.3%, 0.5% and 1%. The optimum results were found in the gel with a concentration of 1% of the 30% ethyl acetate fraction with an average diameter of 18.2 mm inhibition. 30% ethyl acetate fraction gel with 1% stable concentration in storage. Keywords: Zibethinus folium, soxhlet, gel, antibacterial, Staphylococcus aureus

Item Type: Thesis (Undergraduate)
Uncontrolled Keywords: Zibethinus folium, soxhlet, gel, antibacterial, Staphylococcus aureus
Subjects: Q Science > Q Science (General)
Q Science > QK Botany
R Medicine > R Medicine (General)
Divisions: Program Studi > S1 Farmasi
Depositing User: Surya Hadi Prasetyo
Date Deposited: 12 Jan 2022 04:08
Last Modified: 12 Jan 2022 04:08
URI: http://repository.stikes-kartrasa.ac.id/id/eprint/20

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